The BIOS Lab-on-a-Chip Group, MESA+ Institute for Nanotechnology and the Institute for Biomedical Technology at the University of Twente is organizing the first international workshop on label-free biosensing. This workshop is dedicated to direct, or label-free, sensing of biomolecular interactions where different methods and aspects of label-free sensing will be discussed by a wide range of experts. All label-free biosensing systems are comprised of three essential components integrated in one system: i. sensor, ii. sensor surface chemistry and iii. sample fluidics. Each of these topics will be discussed throughout the workshop. Currently the most mature method for label-free sensing of biomolecular interactions is surface plasmon resonance, however, new sensing techniques are emerging with improved sensitivity and in some cases additional information pertaining to the biomolecular interactions. An important aspect of label-free biosensing is the ability to measure the kinetic parameters, such as rate-association and dissociation and equilibrium constants, related to the biomolecular interaction between the immobilized ligand and analyte in the sample serum. These data promise additional insights and understanding into the mechanisms of molecular binding events that will be important for understanding regulatory protein interactions and many others. Some of the LFB 2008 speakers contributed to the new book Handbook of Surface Plasmon Resonance, which will be given to the registered LFB 2008 participants. Additionally, the LFB 2008 workshop is being held between sessions of the ANAC courses read more...

Contact: lfb@lfb2008.com